STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lats1Large tumor suppressor kinase 1. (1028 aa)    
Predicted Functional Partners:
yap1
Yes-associated protein 1.
    
 0.974
sav1
Salvador family WW domain containing protein 1.
    
 0.942
LOC103470272
MOB kinase activator 1A.
    
 0.930
LOC103473359
MOB kinase activator 1Bb.
    
 0.923
stk3
Serine/threonine kinase 3 (STE20 homolog, yeast).
    
0.879
LOC103464816
Uncharacterized protein.
    
0.879
LOC103466678
Si:dkey-266m15.5.
    
 0.855
ENSPREP00000024586
Angiomotin.
    
 0.805
nf2
Neurofibromin 2b (merlin).
    
 
 0.753
wwc1
WW and C2 domain containing 1.
   
 0.734
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.