PLCB1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PLCB1

Phosphoinositide phospholipase C. (1031 aa)

Predicted Functional Partners:

LOC103458452

0.605

LOC103463549

0.605

LOC103470235

0.605

LOC103470237

0.605

edn1

0.569

LOC103463548

0.536

PLCB4

0.492

LOC103473462

0.484

LOC103473463

0.484

LOC103473464

0.484

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103458452	LOC103463548	ENSPREP00000015705	ENSPREP00000017815	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.471
LOC103458452	PLCB1	ENSPREP00000015705	ENSPREP00000023803	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Phosphoinositide phospholipase C.	0.605
LOC103458452	PLCB4	ENSPREP00000015705	ENSPREP00000023730	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.677
LOC103458452	edn1	ENSPREP00000015705	ENSPREP00000012837	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Endothelin 1.	0.465
LOC103463548	LOC103458452	ENSPREP00000017815	ENSPREP00000015705	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	0.471
LOC103463548	LOC103463549	ENSPREP00000017815	ENSPREP00000017763	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).	0.470
LOC103463548	LOC103470235	ENSPREP00000017815	ENSPREP00000029602	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Uncharacterized protein.	0.470
LOC103463548	LOC103470237	ENSPREP00000017815	ENSPREP00000029648	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Guanine nucleotide binding protein (G protein), alpha 14a.	0.470
LOC103463548	PLCB1	ENSPREP00000017815	ENSPREP00000023803	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Phosphoinositide phospholipase C.	0.536
LOC103463548	PLCB4	ENSPREP00000017815	ENSPREP00000023730	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.696
LOC103463548	edn1	ENSPREP00000017815	ENSPREP00000012837	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Endothelin 1.	0.468
LOC103463549	LOC103463548	ENSPREP00000017763	ENSPREP00000017815	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.470
LOC103463549	PLCB1	ENSPREP00000017763	ENSPREP00000023803	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).	Phosphoinositide phospholipase C.	0.605
LOC103463549	PLCB4	ENSPREP00000017763	ENSPREP00000023730	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.677
LOC103463549	edn1	ENSPREP00000017763	ENSPREP00000012837	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).	Endothelin 1.	0.465
LOC103470235	LOC103463548	ENSPREP00000029602	ENSPREP00000017815	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.470
LOC103470235	PLCB1	ENSPREP00000029602	ENSPREP00000023803	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.605
LOC103470235	PLCB4	ENSPREP00000029602	ENSPREP00000023730	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.705
LOC103470235	edn1	ENSPREP00000029602	ENSPREP00000012837	Uncharacterized protein.	Endothelin 1.	0.472
LOC103470237	LOC103463548	ENSPREP00000029648	ENSPREP00000017815	Guanine nucleotide binding protein (G protein), alpha 14a.	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.470