STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103471401Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family. (1681 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.891
LOC103460587
Uncharacterized protein.
    
 0.754
pros1
Protein S.
   
 0.726
mcfd2
Multiple coagulation factor deficiency 2.
     
 0.688
lman1
Lectin, mannose-binding, 1.
    
 0.669
LOC103474919
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.
   
 0.665
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
   
 0.625
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 
 0.621
LOC103469202
Protein Z, vitamin K-dependent plasma glycoprotein a; Belongs to the peptidase S1 family.
   
 0.584
ENSPREP00000011001
Coagulation factor IXb.
   
 0.584
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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