STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pappaPregnancy-associated plasma protein A, pappalysin 1a. (1651 aa)    
Predicted Functional Partners:
stc2
Stanniocalcin 2.
    
 
 0.767
LOC103473346
Insulin-like growth factor binding protein 5a.
    
 0.683
LOC103461867
Insulin-like growth factor binding protein 5a.
    
 0.683
igf1
Insulin-like growth factor 1.
     
 0.570
IGFBP4
Insulin like growth factor binding protein 4.
    
 0.544
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
      
 0.532
ptprc
Protein tyrosine phosphatase receptor type C.
   
 
 0.471
LOC103468846
TIMP metallopeptidase inhibitor 2b.
    
 0.425
LOC103481516
TIMP metallopeptidase inhibitor 2a.
    
 0.425
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 1.
    
 0.425
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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