STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103477517Si:ch211-225p5.8. (215 aa)    
Predicted Functional Partners:
ENSPREP00000024427
IGv domain-containing protein.
  
  
 
0.912
scn1b
Sodium channel, voltage-gated, type I, beta b.
  
  
 
0.903
ENSPREP00000014273
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
     
  0.900
LOC103474423
Sodium channel, voltage-gated, type IV, beta a.
     
  0.900
LOC103475740
Sodium channel, voltage-gated, type IV, beta b.
     
  0.900
prkaca
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
  0.650
LOC103459892
Calcium/calmodulin-dependent protein kinase II alpha.
     
  0.650
LOC103468785
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
     
  0.650
LOC103481524
Protein kinase domain-containing protein.
     
  0.650
LOC103479663
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
     
  0.650
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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