STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scara5Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. (497 aa)    
Predicted Functional Partners:
ENSPREP00000003577
TAP binding protein (tapasin), tandem duplicate 2.
   
 0.584
LOC103465934
C-type lectin domain-containing protein.
  
0.559
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
      
 0.551
LOC103477848
Apolipoprotein Eb.
   
 
 0.519
ENSPREP00000031340
annotation not available
  
 
  0.515
ENSPREP00000033600
Uncharacterized protein.
  
 
  0.510
LOC103479782
Calreticulin.
   
 0.490
LOC103464072
Calreticulin.
   
 0.490
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.479
ENSPREP00000033474
Collagen, type XIX, alpha 1.
  
 
  0.445
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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