STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103458875Tyrosine-protein kinase receptor. (1453 aa)    
Predicted Functional Partners:
ptn
Pleiotrophin.
    
 0.802
grb2
Growth factor receptor-bound protein 2b.
    
 0.776
Mdk
Midkine b.
    
 0.769
ENSPREP00000002283
Uncharacterized protein.
    
 
 0.715
LOC103477907
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
   
 0.689
LOC103476312
Uncharacterized protein.
   
 0.689
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
   
 0.689
gab1
GRB2-associated binding protein 1.
    
 0.665
LOC103480707
PH domain-containing protein.
    
 0.665
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.654
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.