STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103463031Dopamine receptor D4a. (359 aa)    
Predicted Functional Partners:
drd3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
0.660
drd2
Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family.
    
0.660
EPS8L2
EPS8 like 2.
      
 0.643
gabbr2
Gamma-aminobutyric acid (GABA) B receptor, 2.
     
 0.576
grm1
Glutamate receptor, metabotropic 1a.
    
 0.567
ncs1
Neuronal calcium sensor 1a.
   
 0.564
gria3
Glutamate receptor, ionotropic, AMPA 3a.
    
 0.564
gabrd
Gamma-aminobutyric acid (GABA) A receptor, delta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.549
LOC103481657
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.532
GABRB2
Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.522
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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