STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
add1Adducin 1 (alpha). (774 aa)    
Predicted Functional Partners:
xylb
Xylulokinase homolog (H. influenzae).
  
 
 0.841
ENSPREP00000000563
Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family.
  
 
 0.821
enoph1
Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
  
 
 0.761
adi1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family.
  
  
 0.644
LOC103472835
Triosephosphate isomerase.
  
 
 0.639
Tpi1
Triosephosphate isomerase.
  
 
 0.639
add2
Adducin 2 (beta).
  
  
 
0.626
LOC103465250
Adducin 3 (gamma) a.
  
  
 
0.623
adhfe1
Alcohol dehydrogenase iron containing 1.
  
 
 0.616
apaf1
Apoptotic peptidase activating factor 1.
    
 0.578
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.