STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103458871ADAM metallopeptidase domain 17a. (800 aa)    
Predicted Functional Partners:
LOC103473440
Notch receptor 1a.
    
 0.936
notch1
Notch receptor 1b.
    
 0.936
LOC103468742
Notch receptor 3.
    
 0.909
LOC103463625
Notch receptor 2.
    
 0.907
Adam17
Pep_M12B_propep domain-containing protein.
  
  
 
0.902
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.808
LOC103468846
TIMP metallopeptidase inhibitor 2b.
    
 0.548
LOC103481516
TIMP metallopeptidase inhibitor 2a.
    
 0.548
ngfr
Nerve growth factor receptor a (TNFR superfamily, member 16).
     
 0.504
LOC103481795
Nerve growth factor receptor b.
     
 0.504
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.