STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
txndc5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (412 aa)    
Predicted Functional Partners:
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.965
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.965
prdx4
Peroxiredoxin 4.
  
 0.955
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.864
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.754
gak
Cyclin G associated kinase.
    
 0.734
LOC103479782
Calreticulin.
   
 0.714
LOC103464072
Calreticulin.
   
 0.714
PRDX2
Peroxiredoxin 2.
  
 0.660
prdx3
Peroxiredoxin 3.
  
 0.660
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.