STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1268 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
 0.857
arrdc3
Arrestin domain containing 3a.
    
 
 0.817
EGFR
Receptor protein-tyrosine kinase.
   
 0.802
egfr
Receptor protein-tyrosine kinase.
   
 0.802
gja1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.773
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.768
ubb
Uncharacterized protein.
    
 0.730
LOC103466654
Tyrosine-protein kinase receptor.
   
 0.728
LOC103462605
Tyrosine-protein kinase receptor.
   
 0.728
LOC103473189
Uncharacterized protein.
    
 0.725
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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