STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubr4Ubiquitin protein ligase E3 component n-recognin 4. (5216 aa)    
Predicted Functional Partners:
kcmf1
Potassium channel modulatory factor 1.
    
 
 0.854
KCMF1
Potassium channel modulatory factor 1.
    
 
 0.854
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.701
huwe1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
 
 0.696
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae).
   
 
 0.616
uba5
Ubiquitin-like modifier activating enzyme 5.
   
 
 0.616
emc1
ER membrane protein complex subunit 1.
 
    
 0.585
hectd1
HECT domain containing 1.
   
  
 0.579
eprs1
Glutamyl-prolyl-tRNA synthetase.
      
 0.549
ATE1
Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family.
      
 0.549
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.