l2hgdh protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

l2hgdh

L-2-hydroxyglutarate dehydrogenase. (447 aa)

Predicted Functional Partners:

cs

0.970

fh

0.949

LOC103481537

0.890

glud1

0.890

aldh4a1

0.856

LOC103463995

0.843

gad2

0.818

LOC103478943

0.818

ENSPREP00000001718

0.800

gls2

0.800

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001718	LOC103463995	ENSPREP00000001718	ENSPREP00000020471	Uncharacterized protein.	Glutamine synthetase.	0.945
ENSPREP00000001718	LOC103478943	ENSPREP00000001718	ENSPREP00000002937	Uncharacterized protein.	Glutamate decarboxylase 1b.	0.924
ENSPREP00000001718	LOC103481537	ENSPREP00000001718	ENSPREP00000007110	Uncharacterized protein.	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.953
ENSPREP00000001718	aldh4a1	ENSPREP00000001718	ENSPREP00000031480	Uncharacterized protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.916
ENSPREP00000001718	gad2	ENSPREP00000001718	ENSPREP00000001273	Uncharacterized protein.	Glutamate decarboxylase 2.	0.924
ENSPREP00000001718	glud1	ENSPREP00000001718	ENSPREP00000018700	Uncharacterized protein.	Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.953
ENSPREP00000001718	l2hgdh	ENSPREP00000001718	ENSPREP00000026561	Uncharacterized protein.	L-2-hydroxyglutarate dehydrogenase.	0.800
LOC103463995	ENSPREP00000001718	ENSPREP00000020471	ENSPREP00000001718	Glutamine synthetase.	Uncharacterized protein.	0.945
LOC103463995	LOC103478943	ENSPREP00000020471	ENSPREP00000002937	Glutamine synthetase.	Glutamate decarboxylase 1b.	0.913
LOC103463995	LOC103481537	ENSPREP00000020471	ENSPREP00000007110	Glutamine synthetase.	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.963
LOC103463995	aldh4a1	ENSPREP00000020471	ENSPREP00000031480	Glutamine synthetase.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.926
LOC103463995	cs	ENSPREP00000020471	ENSPREP00000033337	Glutamine synthetase.	Citrate synthase; Belongs to the citrate synthase family.	0.401
LOC103463995	gad2	ENSPREP00000020471	ENSPREP00000001273	Glutamine synthetase.	Glutamate decarboxylase 2.	0.913
LOC103463995	gls2	ENSPREP00000020471	ENSPREP00000009351	Glutamine synthetase.	Glutaminase 2a (liver, mitochondrial).	0.945
LOC103463995	glud1	ENSPREP00000020471	ENSPREP00000018700	Glutamine synthetase.	Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.963
LOC103463995	l2hgdh	ENSPREP00000020471	ENSPREP00000026561	Glutamine synthetase.	L-2-hydroxyglutarate dehydrogenase.	0.843
LOC103478943	ENSPREP00000001718	ENSPREP00000002937	ENSPREP00000001718	Glutamate decarboxylase 1b.	Uncharacterized protein.	0.924
LOC103478943	LOC103463995	ENSPREP00000002937	ENSPREP00000020471	Glutamate decarboxylase 1b.	Glutamine synthetase.	0.913
LOC103478943	LOC103481537	ENSPREP00000002937	ENSPREP00000007110	Glutamate decarboxylase 1b.	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.943
LOC103478943	aldh4a1	ENSPREP00000002937	ENSPREP00000031480	Glutamate decarboxylase 1b.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.925