trip12 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

trip12

Thyroid hormone receptor interactor 12. (2062 aa)

Predicted Functional Partners:

UBR1

0.985

Ubr1

0.985

Ubr2

0.985

ENSPREP00000020241

0.985

UBA3

0.978

LOC103465053

0.978

LOC103464541

0.974

uba6

0.974

LOC103467931

0.974

ltn1

0.970

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000020241	LOC103465053	ENSPREP00000020241	ENSPREP00000026705	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Ubiquitin-like modifier activating enzyme 3.	0.444
ENSPREP00000020241	UBA3	ENSPREP00000020241	ENSPREP00000006714	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Ubiquitin like modifier activating enzyme 3.	0.444
ENSPREP00000020241	UBR1	ENSPREP00000020241	ENSPREP00000019682	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.900
ENSPREP00000020241	Ubr2	ENSPREP00000020241	ENSPREP00000020218	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.900
ENSPREP00000020241	ltn1	ENSPREP00000020241	ENSPREP00000022164	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	RING-type domain-containing protein.	0.535
ENSPREP00000020241	trip12	ENSPREP00000020241	ENSPREP00000026747	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Thyroid hormone receptor interactor 12.	0.985
LOC103464541	LOC103465053	ENSPREP00000005578	ENSPREP00000026705	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 3.	0.664
LOC103464541	LOC103467931	ENSPREP00000005578	ENSPREP00000028974	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.902
LOC103464541	UBA3	ENSPREP00000005578	ENSPREP00000006714	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Ubiquitin like modifier activating enzyme 3.	0.664
LOC103464541	trip12	ENSPREP00000005578	ENSPREP00000026747	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Thyroid hormone receptor interactor 12.	0.974
LOC103464541	uba6	ENSPREP00000005578	ENSPREP00000009413	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Ubiquitin like modifier activating enzyme 6.	0.907
LOC103465053	ENSPREP00000020241	ENSPREP00000026705	ENSPREP00000020241	Ubiquitin-like modifier activating enzyme 3.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.444
LOC103465053	LOC103464541	ENSPREP00000026705	ENSPREP00000005578	Ubiquitin-like modifier activating enzyme 3.	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	0.664
LOC103465053	LOC103467931	ENSPREP00000026705	ENSPREP00000028974	Ubiquitin-like modifier activating enzyme 3.	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.664
LOC103465053	UBA3	ENSPREP00000026705	ENSPREP00000006714	Ubiquitin-like modifier activating enzyme 3.	Ubiquitin like modifier activating enzyme 3.	0.900
LOC103465053	UBR1	ENSPREP00000026705	ENSPREP00000019682	Ubiquitin-like modifier activating enzyme 3.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.444
LOC103465053	Ubr1	ENSPREP00000026705	ENSPREP00000019722	Ubiquitin-like modifier activating enzyme 3.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.444
LOC103465053	Ubr2	ENSPREP00000026705	ENSPREP00000020218	Ubiquitin-like modifier activating enzyme 3.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.444
LOC103465053	ltn1	ENSPREP00000026705	ENSPREP00000022164	Ubiquitin-like modifier activating enzyme 3.	RING-type domain-containing protein.	0.486
LOC103465053	trip12	ENSPREP00000026705	ENSPREP00000026747	Ubiquitin-like modifier activating enzyme 3.	Thyroid hormone receptor interactor 12.	0.978