STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGFBR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (544 aa)    
Predicted Functional Partners:
LOC103475119
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.997
tgfb2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.989
tgfb3
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.985
TGFB3
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.985
LOC103482409
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
0.977
LOC103469777
Mothers against decapentaplegic homolog.
   
 0.959
SMAD3
Mothers against decapentaplegic homolog.
   
 0.954
LOC103466539
Mothers against decapentaplegic homolog.
   
 0.954
SMURF2
E3 ubiquitin-protein ligase.
    
 0.953
LOC103468522
E3 ubiquitin-protein ligase.
    
 0.953
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.