STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103476867Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (703 aa)    
Predicted Functional Partners:
Unc79
Uncharacterized protein.
    
 0.768
LOC103461037
RAN binding protein 2.
    
 0.533
rbbp5
Retinoblastoma binding protein 5.
    
 0.465
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.461
LOC103470485
Leucine zipper, putative tumor suppressor 1.
  
 
  
0.459
tep1
Uncharacterized protein.
   
 0.450
LOC103475867
Lysine (K)-specific demethylase 6B, b.
    
 0.449
LOC103475798
Lysine (K)-specific demethylase 6A, like.
    
 0.449
kdm6b
Lysine (K)-specific demethylase 6B, a.
    
 0.449
kdm6a
Lysine (K)-specific demethylase 6A.
    
 0.449
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.