STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptpn3Protein tyrosine phosphatase non-receptor type 3. (1009 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.677
hgs
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 0.621
LOC103459704
Mitogen-activated protein kinase.
    
 0.590
LOC103466203
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.590
stam2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
    
 0.536
stam
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.
    
 0.536
LOC103466877
Mitogen-activated protein kinase.
    
 0.515
LOC103464907
Mitogen-activated protein kinase.
    
 0.515
LOC103467000
Mitogen-activated protein kinase.
    
 0.515
LOC103459765
Mitogen-activated protein kinase.
    
 0.515
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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