STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
telo2TEL2, telomere maintenance 2, homolog (S. cerevisiae). (783 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
   
 
 0.994
tti1
TELO2 interacting protein 1.
    
 
 0.991
atm
Non-specific serine/threonine protein kinase.
    
 
 0.939
ruvbl2
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 
 0.938
LOC103470753
Uncharacterized protein.
    
 
 0.936
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 
 0.929
ENSPREP00000016378
Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.916
Mtor
Serine/threonine-protein kinase TOR.
    
 
 0.916
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.907
smg1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.827
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.