snx2 protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

snx2

Sorting nexin 2. (539 aa)

Predicted Functional Partners:

vps29

0.956

gak

0.948

vps35

0.946

snx6

0.927

snx5

0.927

vps26a

0.806

igf2r

0.733

LOC103476205

0.682

vps26b

0.682

LOC103465350

0.674

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103465350	igf2r	ENSPREP00000022741	ENSPREP00000026805	Si:dkey-28n18.9.	Insulin-like growth factor 2 receptor.	0.682
LOC103465350	snx2	ENSPREP00000022741	ENSPREP00000027486	Si:dkey-28n18.9.	Sorting nexin 2.	0.674
LOC103465350	vps29	ENSPREP00000022741	ENSPREP00000008393	Si:dkey-28n18.9.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.505
LOC103465350	vps35	ENSPREP00000022741	ENSPREP00000032772	Si:dkey-28n18.9.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.518
LOC103476205	snx2	ENSPREP00000015927	ENSPREP00000027486	Uncharacterized protein.	Sorting nexin 2.	0.682
LOC103476205	snx5	ENSPREP00000015927	ENSPREP00000009725	Uncharacterized protein.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.425
LOC103476205	snx6	ENSPREP00000015927	ENSPREP00000005505	Uncharacterized protein.	Sorting nexin 6.	0.425
LOC103476205	vps26a	ENSPREP00000015927	ENSPREP00000021737	Uncharacterized protein.	VPS26, retromer complex component A.	0.960
LOC103476205	vps26b	ENSPREP00000015927	ENSPREP00000016547	Uncharacterized protein.	VPS26, retromer complex component B.	0.900
LOC103476205	vps29	ENSPREP00000015927	ENSPREP00000008393	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.966
LOC103476205	vps35	ENSPREP00000015927	ENSPREP00000032772	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.979
gak	igf2r	ENSPREP00000012671	ENSPREP00000026805	Cyclin G associated kinase.	Insulin-like growth factor 2 receptor.	0.960
gak	snx2	ENSPREP00000012671	ENSPREP00000027486	Cyclin G associated kinase.	Sorting nexin 2.	0.948
gak	vps29	ENSPREP00000012671	ENSPREP00000008393	Cyclin G associated kinase.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.480
gak	vps35	ENSPREP00000012671	ENSPREP00000032772	Cyclin G associated kinase.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.718
igf2r	LOC103465350	ENSPREP00000026805	ENSPREP00000022741	Insulin-like growth factor 2 receptor.	Si:dkey-28n18.9.	0.682
igf2r	gak	ENSPREP00000026805	ENSPREP00000012671	Insulin-like growth factor 2 receptor.	Cyclin G associated kinase.	0.960
igf2r	snx2	ENSPREP00000026805	ENSPREP00000027486	Insulin-like growth factor 2 receptor.	Sorting nexin 2.	0.733
igf2r	snx5	ENSPREP00000026805	ENSPREP00000009725	Insulin-like growth factor 2 receptor.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.775
igf2r	snx6	ENSPREP00000026805	ENSPREP00000005505	Insulin-like growth factor 2 receptor.	Sorting nexin 6.	0.780