STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lrp6LDL receptor related protein 6. (628 aa)    
Predicted Functional Partners:
sost
Sclerostin.
    
 0.972
dkk2
Dickkopf WNT signaling pathway inhibitor 2.
    
 0.951
LOC103480964
Dickkopf_N domain-containing protein.
    
 0.951
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.932
wnt1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.914
bambi
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.
    
 0.911
ENSPREP00000033823
Uncharacterized protein.
 
  
 0.906
serpinf1
SERPIN domain-containing protein; Belongs to the serpin family.
    
 0.905
ENSPREP00000005844
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.903
Fzd8
Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.903
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.