LOC103467457 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC103467457

Protein kinase domain-containing protein. (548 aa)

Predicted Functional Partners:

cdc6

0.811

CDC25B

0.784

orc2

0.759

LOC103474790

0.748

ccnb3

0.748

wdr41

0.748

ccnb1

0.748

ccna2

0.747

ccna1

0.747

cdc23

0.732

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC25B	LOC103467457	ENSPREP00000010131	ENSPREP00000027760	Cell division cycle 25B.	Protein kinase domain-containing protein.	0.784
CDC25B	LOC103474790	ENSPREP00000010131	ENSPREP00000008318	Cell division cycle 25B.	Cyclin N-terminal domain containing 2; Belongs to the cyclin family.	0.853
CDC25B	ccna1	ENSPREP00000010131	ENSPREP00000016983	Cell division cycle 25B.	Cyclin A1; Belongs to the cyclin family.	0.842
CDC25B	ccna2	ENSPREP00000010131	ENSPREP00000010495	Cell division cycle 25B.	Cyclin A2; Belongs to the cyclin family.	0.842
CDC25B	ccnb1	ENSPREP00000010131	ENSPREP00000029917	Cell division cycle 25B.	Cyclin B1; Belongs to the cyclin family.	0.893
CDC25B	ccnb3	ENSPREP00000010131	ENSPREP00000015076	Cell division cycle 25B.	Cyclin B3; Belongs to the cyclin family.	0.847
CDC25B	cdc6	ENSPREP00000010131	ENSPREP00000032222	Cell division cycle 25B.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.559
CDC25B	orc2	ENSPREP00000010131	ENSPREP00000031604	Cell division cycle 25B.	Origin recognition complex, subunit 2.	0.938
CDC25B	wdr41	ENSPREP00000010131	ENSPREP00000027833	Cell division cycle 25B.	WD repeat domain 41.	0.847
LOC103467457	CDC25B	ENSPREP00000027760	ENSPREP00000010131	Protein kinase domain-containing protein.	Cell division cycle 25B.	0.784
LOC103467457	LOC103474790	ENSPREP00000027760	ENSPREP00000008318	Protein kinase domain-containing protein.	Cyclin N-terminal domain containing 2; Belongs to the cyclin family.	0.748
LOC103467457	ccna1	ENSPREP00000027760	ENSPREP00000016983	Protein kinase domain-containing protein.	Cyclin A1; Belongs to the cyclin family.	0.747
LOC103467457	ccna2	ENSPREP00000027760	ENSPREP00000010495	Protein kinase domain-containing protein.	Cyclin A2; Belongs to the cyclin family.	0.747
LOC103467457	ccnb1	ENSPREP00000027760	ENSPREP00000029917	Protein kinase domain-containing protein.	Cyclin B1; Belongs to the cyclin family.	0.748
LOC103467457	ccnb3	ENSPREP00000027760	ENSPREP00000015076	Protein kinase domain-containing protein.	Cyclin B3; Belongs to the cyclin family.	0.748
LOC103467457	cdc23	ENSPREP00000027760	ENSPREP00000034182	Protein kinase domain-containing protein.	CDC23 (cell division cycle 23, yeast, homolog).	0.732
LOC103467457	cdc6	ENSPREP00000027760	ENSPREP00000032222	Protein kinase domain-containing protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.811
LOC103467457	orc2	ENSPREP00000027760	ENSPREP00000031604	Protein kinase domain-containing protein.	Origin recognition complex, subunit 2.	0.759
LOC103467457	wdr41	ENSPREP00000027760	ENSPREP00000027833	Protein kinase domain-containing protein.	WD repeat domain 41.	0.748
LOC103474790	CDC25B	ENSPREP00000008318	ENSPREP00000010131	Cyclin N-terminal domain containing 2; Belongs to the cyclin family.	Cell division cycle 25B.	0.853