STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103474461Cullin 3; Belongs to the cullin family. (767 aa)    
Predicted Functional Partners:
spopl
Speckle type BTB/POZ protein like b.
   
 0.993
SPOP
Speckle type BTB/POZ protein.
   
 0.993
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.987
ubxn7
UBX domain protein 7.
   
 0.984
sufu
Suppressor of fused homolog.
     
 0.966
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
   
 0.960
fbxw11
F-box and WD repeat domain containing 11a.
   
 0.951
gli2
GLI family zinc finger 2a.
    
 0.950
gli1
GLI family zinc finger 1.
    
 0.950
skp2
F-box domain-containing protein.
    
 0.938
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.