STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbk1TANK-binding kinase 1. (703 aa)    
Predicted Functional Partners:
sting1
Transmembrane protein 173.
   
 0.995
LOC103481249
Interferon regulatory factor 3.
   
 0.993
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.991
tank
TRAF family member-associated NFKB activator.
   
 0.991
optn
Optineurin.
   
 0.990
sqstm1
Sequestosome 1.
    
 0.974
irf7
Interferon regulatory factor 7.
   
 0.974
Calcoco2
SKICH domain-containing protein.
    
 0.964
LOC103474866
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
 0.930
LOC103480184
V-rel avian reticuloendotheliosis viral oncogene homolog A.
   
 0.926
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.