STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrk2Neurotrophic tyrosine kinase, receptor, type 2a. (469 aa)    
Predicted Functional Partners:
LOC103467432
Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.
    
 0.901
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
   
 0.899
ENSPREP00000007409
NGF domain-containing protein; Belongs to the NGF-beta family.
    
 0.889
ntf3
Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.
    
 0.886
grb2
Growth factor receptor-bound protein 2b.
    
 0.837
LOC103464694
Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.
     
 0.809
igf1
Insulin-like growth factor 1.
    
 0.771
LOC103474014
Ephrin-A5a; Belongs to the ephrin family.
    
 0.748
fgf22
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.748
EFNA5
Ephrin A5; Belongs to the ephrin family.
    
 0.748
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.