STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
evplEnvoplakin a. (1957 aa)    
Predicted Functional Partners:
ppl
Periplakin.
  
 
0.669
ENSPREP00000007561
Kazrin, periplakin interacting protein b.
    
 0.537
KAZN
Kazrin, periplakin interacting protein a.
    
 0.537
LOC103479638
Desmocollin 2 like; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.523
LOC103466878
Keratin 5; Belongs to the intermediate filament family.
   
 0.497
LOC103465321
Junction plakoglobin a.
   
 0.474
eny2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.433
sptan1
Spectrin alpha, non-erythrocytic 1.
   
 0.424
ENSPREP00000015831
Uncharacterized protein.
    
 0.422
ENSPREP00000015870
Uncharacterized protein.
    
 0.422
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.