lrrc56 protein (Poecilia reticulata) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

lrrc56

Leucine rich repeat containing 56. (621 aa)

Predicted Functional Partners:

dusp8

0.662

gins2

0.558

pih1d2

0.556

pih1d1

0.556

LOC103462943

0.554

ENSPREP00000002714

0.554

ENSPREP00000003616

0.554

adgrl1

0.554

LOC103479721

0.554

LOC103469185

0.554

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002714	lrrc56	ENSPREP00000002714	ENSPREP00000028554	SUEL-type lectin domain-containing protein.	Leucine rich repeat containing 56.	0.554
ENSPREP00000003616	lrrc56	ENSPREP00000003616	ENSPREP00000028554	Uncharacterized protein.	Leucine rich repeat containing 56.	0.554
LOC103462943	lrrc56	ENSPREP00000000424	ENSPREP00000028554	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 56.	0.554
LOC103469185	lrrc56	ENSPREP00000015822	ENSPREP00000028554	Adhesion G protein-coupled receptor L3.1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 56.	0.554
LOC103479721	lrrc56	ENSPREP00000014055	ENSPREP00000028554	Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 56.	0.554
adgrl1	lrrc56	ENSPREP00000006738	ENSPREP00000028554	Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat containing 56.	0.554
dusp8	lrrc56	ENSPREP00000029845	ENSPREP00000028554	Dual specificity phosphatase 8a.	Leucine rich repeat containing 56.	0.662
gins2	lrrc56	ENSPREP00000019023	ENSPREP00000028554	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	Leucine rich repeat containing 56.	0.558
lrrc56	ENSPREP00000002714	ENSPREP00000028554	ENSPREP00000002714	Leucine rich repeat containing 56.	SUEL-type lectin domain-containing protein.	0.554
lrrc56	ENSPREP00000003616	ENSPREP00000028554	ENSPREP00000003616	Leucine rich repeat containing 56.	Uncharacterized protein.	0.554
lrrc56	LOC103462943	ENSPREP00000028554	ENSPREP00000000424	Leucine rich repeat containing 56.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.554
lrrc56	LOC103469185	ENSPREP00000028554	ENSPREP00000015822	Leucine rich repeat containing 56.	Adhesion G protein-coupled receptor L3.1; Belongs to the G-protein coupled receptor 2 family.	0.554
lrrc56	LOC103479721	ENSPREP00000028554	ENSPREP00000014055	Leucine rich repeat containing 56.	Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.	0.554
lrrc56	adgrl1	ENSPREP00000028554	ENSPREP00000006738	Leucine rich repeat containing 56.	Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.	0.554
lrrc56	dusp8	ENSPREP00000028554	ENSPREP00000029845	Leucine rich repeat containing 56.	Dual specificity phosphatase 8a.	0.662
lrrc56	gins2	ENSPREP00000028554	ENSPREP00000019023	Leucine rich repeat containing 56.	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	0.558
lrrc56	pih1d1	ENSPREP00000028554	ENSPREP00000018017	Leucine rich repeat containing 56.	PIH1 domain containing 1.	0.556
lrrc56	pih1d2	ENSPREP00000028554	ENSPREP00000015760	Leucine rich repeat containing 56.	PIH1 domain containing 2.	0.556
pih1d1	lrrc56	ENSPREP00000018017	ENSPREP00000028554	PIH1 domain containing 1.	Leucine rich repeat containing 56.	0.556
pih1d1	pih1d2	ENSPREP00000018017	ENSPREP00000015760	PIH1 domain containing 1.	PIH1 domain containing 2.	0.549

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.83

expected number of edges:

11

PPI enrichment p-value:

8.85e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015288

Porin activity

2 of 5

2.96

1.15

0.0097

GO:0008308

Voltage-gated anion channel activity

2 of 15

2.48

0.85

0.0313

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:32899810

(2020) Screening for the Proteins That Can Interact with Grouper Nervous Necrosis Virus Capsid Protein.

2 of 20

2.36

0.84

0.0325

PMID:27571066

(2016) Sexually Dimorphic Gene Expression Associated with Growth and Reproduction of Tongue Sole (Cynoglossus semilaevis) Revealed by Brain Transcriptome Analysis.

2 of 26

2.25

0.83

0.0325

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:38678

Mixed, incl. Notochord cell development, and AB hydrolase 4, conserved site

2 of 5

2.96

1.0

0.0180

CL:22657

ATP:ADP antiporter activity, and Porin activity

2 of 11

2.62

0.84

0.0335

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pret04216

Ferroptosis

2 of 46

2.0

0.82

0.0319

Tissue Expression (TISSUES)

tissue

description

count in network

strength

signal

false discovery rate

BTO:0001630

Right ventricle

2 of 179

1.41

0.76

0.0242

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01459

Eukaryotic porin

2 of 8

2.76

1.0

0.0176

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001925

Porin, eukaryotic type

2 of 5

2.96

0.91

0.0256

IPR027246

Eukaryotic porin/Tom40

2 of 8

2.76

0.89

0.0274

IPR023614

Porin domain superfamily

2 of 8

2.76

0.89

0.0274

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