STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdx1Pancreatic and duodenal homeobox 1. (255 aa)    
Predicted Functional Partners:
spopl
Speckle type BTB/POZ protein like b.
    
   0.732
SPOP
Speckle type BTB/POZ protein.
    
   0.732
hnf1a
HNF1 homeobox a.
   
  
 0.645
LOC103476384
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.633
ENSPREP00000030771
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.633
ENSPREP00000029608
CALCITONIN domain-containing protein.
     
 0.599
ptf1a
Pancreas associated transcription factor 1a.
   
 
 0.558
ENSPREP00000021170
Uncharacterized protein.
      
 0.539
foxa2
Forkhead box A2.
    
 0.524
foxa1
Fork-head domain-containing protein.
    
 0.524
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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