STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nkx2-5NK2 homeobox 5. (316 aa)    
Predicted Functional Partners:
mef2b
Myocyte enhancer factor 2b.
    
 
 0.919
gata4
GATA binding protein 4.
   
 0.887
LOC103473796
T-box transcription factor 5a.
   
 
 0.862
gata6
GATA binding protein 6.
   
 0.854
LOC103466925
GATA binding protein 5.
   
 0.846
LOC103470367
Uncharacterized protein.
   
 
 0.813
mef2c
Myocyte enhancer factor 2cb.
    
 
 0.781
tbx4
T-box transcription factor 4.
   
 
 0.757
hand2
Heart and neural crest derivatives expressed 2.
   
 
 0.750
LOC103462206
MADS-box domain-containing protein.
    
 
 0.734
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.