STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thTyrosine hydroxylase. (521 aa)    
Predicted Functional Partners:
pcbd1
Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.
  
 0.977
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.977
qdpr
Quinoid dihydropteridine reductase a.
    
 0.956
got2
Aspartate aminotransferase.
  
 
 0.943
GOT1
Aspartate aminotransferase.
  
 
 0.938
spr
Sepiapterin reductase b.
   
 
 0.937
TYR
Tyrosinase.
     
 0.930
tat
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.925
LOC103474367
Amine oxidase.
     
 0.918
TPO
Thyroid peroxidase.
     
 0.916
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.