scap protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

scap

SREBF chaperone. (1264 aa)

Predicted Functional Partners:

srebf1

0.941

Srebf2

0.941

ENSPREP00000024568

0.941

insig1

0.893

insig2

0.893

npc2

0.883

mbtps1

0.768

LOC103457471

0.765

mbtps2

0.549

sycp3

0.528

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000024568	Srebf2	ENSPREP00000024568	ENSPREP00000024531	BHLH domain-containing protein.	Uncharacterized protein.	0.900
ENSPREP00000024568	insig1	ENSPREP00000024568	ENSPREP00000013287	BHLH domain-containing protein.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.426
ENSPREP00000024568	mbtps1	ENSPREP00000024568	ENSPREP00000000957	BHLH domain-containing protein.	Membrane-bound transcription factor peptidase, site 1.	0.660
ENSPREP00000024568	mbtps2	ENSPREP00000024568	ENSPREP00000033833	BHLH domain-containing protein.	Membrane-bound transcription factor peptidase, site 2.	0.749
ENSPREP00000024568	scap	ENSPREP00000024568	ENSPREP00000029624	BHLH domain-containing protein.	SREBF chaperone.	0.941
ENSPREP00000024568	srebf1	ENSPREP00000024568	ENSPREP00000007886	BHLH domain-containing protein.	Sterol regulatory element binding transcription factor 1.	0.420
LOC103457471	mbtps2	ENSPREP00000008659	ENSPREP00000033833	MYCN proto-oncogene, bHLH transcription factor.	Membrane-bound transcription factor peptidase, site 2.	0.728
LOC103457471	scap	ENSPREP00000008659	ENSPREP00000029624	MYCN proto-oncogene, bHLH transcription factor.	SREBF chaperone.	0.765
Srebf2	ENSPREP00000024568	ENSPREP00000024531	ENSPREP00000024568	Uncharacterized protein.	BHLH domain-containing protein.	0.900
Srebf2	insig1	ENSPREP00000024531	ENSPREP00000013287	Uncharacterized protein.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.426
Srebf2	mbtps1	ENSPREP00000024531	ENSPREP00000000957	Uncharacterized protein.	Membrane-bound transcription factor peptidase, site 1.	0.660
Srebf2	mbtps2	ENSPREP00000024531	ENSPREP00000033833	Uncharacterized protein.	Membrane-bound transcription factor peptidase, site 2.	0.749
Srebf2	scap	ENSPREP00000024531	ENSPREP00000029624	Uncharacterized protein.	SREBF chaperone.	0.941
insig1	ENSPREP00000024568	ENSPREP00000013287	ENSPREP00000024568	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	BHLH domain-containing protein.	0.426
insig1	Srebf2	ENSPREP00000013287	ENSPREP00000024531	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Uncharacterized protein.	0.426
insig1	scap	ENSPREP00000013287	ENSPREP00000029624	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	SREBF chaperone.	0.893
insig1	srebf1	ENSPREP00000013287	ENSPREP00000007886	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 1.	0.444
insig2	scap	ENSPREP00000022714	ENSPREP00000029624	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	SREBF chaperone.	0.893
mbtps1	ENSPREP00000024568	ENSPREP00000000957	ENSPREP00000024568	Membrane-bound transcription factor peptidase, site 1.	BHLH domain-containing protein.	0.660
mbtps1	Srebf2	ENSPREP00000000957	ENSPREP00000024531	Membrane-bound transcription factor peptidase, site 1.	Uncharacterized protein.	0.660