STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103467398Uncharacterized protein. (210 aa)    
Predicted Functional Partners:
rock2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.968
ARHGEF2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
   
 0.964
DIAPH1
Diaphanous related formin 1.
   
 0.964
diaph2
Diaphanous-related formin 2.
   
 0.960
arhgap5
Rho GTPase activating protein 5.
    
 0.959
arhgef1
Rho guanine nucleotide exchange factor (GEF) 1b.
   
 0.959
LOC103475743
Rho GTPase activating protein 35b.
    
 0.959
arhgap35
Uncharacterized protein.
    
 0.959
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11.
   
 0.955
ENSPREP00000021285
DH domain-containing protein.
   
 0.955
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.