STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dbr1Debranching RNA lariats 1. (538 aa)    
Predicted Functional Partners:
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38.
    
 
 0.856
cwf19l1
CWF19 like cell cycle control factor 1.
   
 
0.771
xpo5
Exportin 5.
   
  
 0.658
mettl9
Methyltransferase like 9.
 
      0.638
prpf18
PRP18 pre-mRNA processing factor 18 homolog (yeast).
    
 
 0.564
cwf19l2
CWF19 like cell cycle control factor 2.
   
  
 0.561
drosha
Drosha ribonuclease III.
   
  
 0.555
dicer1
Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.
   
  
 0.554
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
      
 0.549
xab2
XPA binding protein 2.
   
  
 0.548
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.