STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)    
Predicted Functional Partners:
icmt
Protein-S-isoprenylcysteine O-methyltransferase.
    
 0.964
fnta
Farnesyltransferase, CAAX box, alpha.
     
 0.963
rce1
Ras converting CAAX endopeptidase 1a.
    
 
 0.757
ENSPREP00000010801
Uncharacterized protein.
    
 
 0.757
grpel1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.742
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
  
 0.714
ENSPREP00000028967
Heat shock 10 protein 1; Belongs to the GroES chaperonin family.
  
  
 0.644
oma1
OMA1 zinc metallopeptidase.
      
 0.597
dars2
Aspartyl-tRNA synthetase 2, mitochondrial.
  
  
 0.595
lmna
Lamin A; Belongs to the intermediate filament family.
    
 
 0.565
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.