STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTN4Actinin alpha 4. (898 aa)    
Predicted Functional Partners:
vcl
Vinculin b.
   
 0.961
LOC103476978
Vinculin a.
   
 0.961
LOC103462148
Uncharacterized protein.
   
 0.947
ctnna2
Catenin (cadherin-associated protein), alpha 2.
   
 0.928
ENSPREP00000004733
Uncharacterized protein.
   
 0.924
magi1
Membrane associated guanylate kinase, WW and PDZ domain containing 1b.
    
 0.917
micall2
Mical-like 2a.
    
0.913
ENSPREP00000032344
Calponin-homology (CH) domain-containing protein.
    
 0.907
LOC103467714
MAGI family member, X-linked b.
    
 0.902
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
   
 
 0.902
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.