STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sec22cSEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family. (312 aa)    
Predicted Functional Partners:
stx5
Syntaxin 5A; Belongs to the syntaxin family.
   
 0.950
bet1
Bet1 golgi vesicular membrane trafficking protein.
   
 0.938
ykt6
YKT6 v-SNARE homolog (S. cerevisiae); Belongs to the synaptobrevin family.
    
 0.936
gosr2
Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
    
 0.935
stx18
Syntaxin 18.
   
 0.906
use1
Unconventional SNARE in the ER 1 homolog (S. cerevisiae).
    
 0.876
rint1
RAD50 interactor 1.
    
 0.870
zw10
Zw10 kinetochore protein.
    
 0.857
vti1a
Vesicle transport through interaction with t-SNAREs 1A.
   
 
 0.851
LOC103464900
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 0.833
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.