STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000030771Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (65 aa)    
Predicted Functional Partners:
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
    
 0.933
LOC103466654
Tyrosine-protein kinase receptor.
    
 0.766
LOC103462605
Tyrosine-protein kinase receptor.
    
 0.766
insr
Insulin receptor a.
    
 0.766
ENSPREP00000025003
Uncharacterized protein.
    
 0.766
gcg
Glucagon b.
   
 
 0.728
ENSPREP00000008079
Uncharacterized protein.
    
 0.722
NRDC
Nardilysin b (N-arginine dibasic convertase); Belongs to the peptidase M16 family.
    
 0.722
nrdc
Nardilysin a (N-arginine dibasic convertase); Belongs to the peptidase M16 family.
    
 0.722
egf
Epidermal growth factor.
     
 0.718
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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