RIDA protein (Poecilia reticulata) - STRING interaction network

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

RIDA

Reactive intermediate imine deaminase A homolog. (136 aa)

Predicted Functional Partners:

hacl1

0.708

ilvbl

0.708

cnot9

0.697

cnot4

0.695

cnot1

0.683

eef2

0.664

LOC103479455

0.664

LOC103460681

0.662

SDS

0.662

LOC103459528

0.643

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103459528	RIDA	ENSPREP00000011705	ENSPREP00000030965	Si:ch73-263o4.3.	Reactive intermediate imine deaminase A homolog.	0.643
LOC103459528	hacl1	ENSPREP00000011705	ENSPREP00000002472	Si:ch73-263o4.3.	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family.	0.684
LOC103459528	ilvbl	ENSPREP00000011705	ENSPREP00000007371	Si:ch73-263o4.3.	IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family.	0.684
LOC103460681	RIDA	ENSPREP00000008434	ENSPREP00000030965	Serine dehydratase-like.	Reactive intermediate imine deaminase A homolog.	0.662
LOC103460681	SDS	ENSPREP00000008434	ENSPREP00000012057	Serine dehydratase-like.	Serine dehydratase.	0.903
LOC103460681	hacl1	ENSPREP00000008434	ENSPREP00000002472	Serine dehydratase-like.	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family.	0.684
LOC103460681	ilvbl	ENSPREP00000008434	ENSPREP00000007371	Serine dehydratase-like.	IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family.	0.684
LOC103479455	RIDA	ENSPREP00000026101	ENSPREP00000030965	Eukaryotic translation elongation factor 2b.	Reactive intermediate imine deaminase A homolog.	0.664
RIDA	LOC103459528	ENSPREP00000030965	ENSPREP00000011705	Reactive intermediate imine deaminase A homolog.	Si:ch73-263o4.3.	0.643
RIDA	LOC103460681	ENSPREP00000030965	ENSPREP00000008434	Reactive intermediate imine deaminase A homolog.	Serine dehydratase-like.	0.662
RIDA	LOC103479455	ENSPREP00000030965	ENSPREP00000026101	Reactive intermediate imine deaminase A homolog.	Eukaryotic translation elongation factor 2b.	0.664
RIDA	SDS	ENSPREP00000030965	ENSPREP00000012057	Reactive intermediate imine deaminase A homolog.	Serine dehydratase.	0.662
RIDA	cnot1	ENSPREP00000030965	ENSPREP00000027855	Reactive intermediate imine deaminase A homolog.	CCR4-NOT transcription complex, subunit 1.	0.683
RIDA	cnot4	ENSPREP00000030965	ENSPREP00000012043	Reactive intermediate imine deaminase A homolog.	CCR4-NOT transcription complex, subunit 4a.	0.695
RIDA	cnot9	ENSPREP00000030965	ENSPREP00000001000	Reactive intermediate imine deaminase A homolog.	CCR4-NOT transcription complex subunit 9.	0.697
RIDA	eef2	ENSPREP00000030965	ENSPREP00000012263	Reactive intermediate imine deaminase A homolog.	Tr-type G domain-containing protein.	0.664
RIDA	hacl1	ENSPREP00000030965	ENSPREP00000002472	Reactive intermediate imine deaminase A homolog.	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family.	0.708
RIDA	ilvbl	ENSPREP00000030965	ENSPREP00000007371	Reactive intermediate imine deaminase A homolog.	IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family.	0.708
SDS	LOC103460681	ENSPREP00000012057	ENSPREP00000008434	Serine dehydratase.	Serine dehydratase-like.	0.903
SDS	RIDA	ENSPREP00000012057	ENSPREP00000030965	Serine dehydratase.	Reactive intermediate imine deaminase A homolog.	0.662

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Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.928

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0001676

Long-chain fatty acid metabolic process

6 of 11

2.31

4.35

1.21e-09

GO:0032787

Monocarboxylic acid metabolic process

8 of 188

1.2

1.45

2.44e-06

GO:0044255

Cellular lipid metabolic process

7 of 158

1.22

1.37

1.53e-05

GO:0019427

acetyl-CoA biosynthetic process from acetate

2 of 4

2.27

1.01

0.0137

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016874

Ligase activity

8 of 137

1.34

1.85

2.41e-07

GO:0016405

CoA-ligase activity

3 of 10

2.05

1.44

0.0016

GO:0016878

Acid-thiol ligase activity

3 of 12

1.97

1.41

0.0017

GO:0016208

AMP binding

2 of 4

2.27

1.2

0.0059

GO:0003987

acetate-CoA ligase activity

2 of 4

2.27

1.2

0.0059

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4084

Long-chain fatty acid metabolic process, and Phosphate acyltransferases

4 of 7

2.33

2.9

2.28e-06

CL:3908

Mixed, incl. Valine, leucine and isoleucine degradation, and Fatty acid metabolic process

7 of 95

1.44

1.92

1.44e-06

CL:5282

Mixed, incl. Sphingolipid metabolic process, and Helix-turn-helix XRE-family like proteins

2 of 6

2.09

0.85

0.0255

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0436

Ligase

8 of 92

1.51

2.54

3.37e-09

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13193

AMP-binding enzyme C-terminal domain

7 of 10

2.41

5.93

5.40e-13

PF00501

AMP-binding enzyme

8 of 17

2.24

5.92

5.86e-14

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000873

AMP-dependent synthetase/ligase domain

8 of 17

2.24

5.76

1.54e-13

IPR025110

AMP-binding enzyme, C-terminal domain

7 of 10

2.41

5.75

1.42e-12

IPR045851

AMP-binding enzyme, C-terminal domain superfamily

7 of 12

2.34

5.51

2.44e-12

IPR020845

AMP-binding, conserved site

7 of 12

2.34

5.51

2.44e-12

IPR042099

ANL, N-terminal domain

7 of 16

2.21

5.08

7.11e-12

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