STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
get4Guided entry of tail-anchored proteins factor 4. (323 aa)    
Predicted Functional Partners:
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
    
 0.994
bag6
BCL2 associated athanogene 6.
    
 0.977
sgta
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha.
   
 0.909
sgtb
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta.
   
 0.909
LOC103470505
Ubiquitin like 4A.
    
 0.894
Rad23a
Ubiquitin-like domain-containing protein.
    
 0.853
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
    
 0.853
ttc33
Tetratricopeptide repeat domain 33.
   
 0.851
get1
Guided entry of tail-anchored proteins factor 1.
    
 0.724
rnf126
RING-type domain-containing protein.
   
 
 0.667
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.