rnf139 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rnf139

Ring finger protein 139. (701 aa)

Predicted Functional Partners:

os9

0.775

erlec1

0.775

Katnal2

0.774

derl1

0.765

LOC103469840

0.748

derl2

0.748

sel1l

0.742

hm13

0.731

ube2g2

0.725

LOC103482061

0.699

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Katnal2	LOC103469840	ENSPREP00000007118	ENSPREP00000005741	Katanin p60 subunit A-like 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.807
Katnal2	LOC103482061	ENSPREP00000007118	ENSPREP00000000442	Katanin p60 subunit A-like 2.	Zgc:136908; Belongs to the AAA ATPase family.	0.413
Katnal2	derl1	ENSPREP00000007118	ENSPREP00000020837	Katanin p60 subunit A-like 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.808
Katnal2	derl2	ENSPREP00000007118	ENSPREP00000009081	Katanin p60 subunit A-like 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.807
Katnal2	erlec1	ENSPREP00000007118	ENSPREP00000033924	Katanin p60 subunit A-like 2.	Endoplasmic reticulum lectin 1.	0.683
Katnal2	os9	ENSPREP00000007118	ENSPREP00000025152	Katanin p60 subunit A-like 2.	OS9 endoplasmic reticulum lectin.	0.683
Katnal2	rnf139	ENSPREP00000007118	ENSPREP00000031265	Katanin p60 subunit A-like 2.	Ring finger protein 139.	0.774
Katnal2	sel1l	ENSPREP00000007118	ENSPREP00000019588	Katanin p60 subunit A-like 2.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.474
LOC103469840	Katnal2	ENSPREP00000005741	ENSPREP00000007118	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Katanin p60 subunit A-like 2.	0.807
LOC103469840	LOC103482061	ENSPREP00000005741	ENSPREP00000000442	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Zgc:136908; Belongs to the AAA ATPase family.	0.842
LOC103469840	derl1	ENSPREP00000005741	ENSPREP00000020837	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.992
LOC103469840	derl2	ENSPREP00000005741	ENSPREP00000009081	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.901
LOC103469840	erlec1	ENSPREP00000005741	ENSPREP00000033924	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.933
LOC103469840	hm13	ENSPREP00000005741	ENSPREP00000007435	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Histocompatibility (minor) 13.	0.405
LOC103469840	os9	ENSPREP00000005741	ENSPREP00000025152	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.933
LOC103469840	rnf139	ENSPREP00000005741	ENSPREP00000031265	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ring finger protein 139.	0.748
LOC103469840	sel1l	ENSPREP00000005741	ENSPREP00000019588	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.943
LOC103469840	ube2g2	ENSPREP00000005741	ENSPREP00000027103	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast).	0.440
LOC103482061	Katnal2	ENSPREP00000000442	ENSPREP00000007118	Zgc:136908; Belongs to the AAA ATPase family.	Katanin p60 subunit A-like 2.	0.413
LOC103482061	LOC103469840	ENSPREP00000000442	ENSPREP00000005741	Zgc:136908; Belongs to the AAA ATPase family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.842