STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103456566Mitogen-activated protein kinase kinase kinase 22. (618 aa)    
Predicted Functional Partners:
LOC103458433
Non-specific serine/threonine protein kinase.
  
 
0.939
pak2
Non-specific serine/threonine protein kinase.
    
0.936
map3k4
Mitogen-activated protein kinase kinase kinase 4.
    
0.933
LOC103481589
Mitogen-activated protein kinase kinase 6.
  
0.917
Map3k2
Protein kinase domain-containing protein.
     
 
0.900
ccm2
CCM2 scaffold protein.
    
 0.816
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.787
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
  
0.778
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
0.691
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
  
0.689
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.