STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103476491Pellino E3 ubiquitin protein ligase 1b. (426 aa)    
Predicted Functional Partners:
ENSPREP00000018760
Protein kinase domain-containing protein.
    
 0.799
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.758
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.701
LOC103479635
Death domain-containing protein.
    
 0.603
LOC103466013
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.543
ube2n
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.542
LOC103466094
Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.542
ENSPREP00000001588
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.462
LOC103467757
Transmembrane protein 189.
    
 0.462
ube2v2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.462
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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