STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPXEosinophil peroxidase. (875 aa)    
Predicted Functional Partners:
LOC103456660
Cytochrome b-245, beta polypeptide (chronic granulomatous disease).
   
 
 0.614
nox5
NADPH oxidase, EF-hand calcium binding domain 5.
   
 
 0.614
nos1
Nitric oxide synthase 1 (neuronal).
    
 
 0.604
LOC103462573
Cytochrome b-245, alpha polypeptide.
   
  
 0.600
tdo2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
      
 0.597
LOC103460371
Cytochrome c-1.
      
 0.597
Dock2
DHR-2 domain-containing protein; Belongs to the DOCK family.
      
 0.597
lcp1
Lymphocyte cytosolic protein 1 (L-plastin).
   
  
 0.549
LOC103479005
Peroxiredoxin 1.
      
 0.516
spi1
Spi-1 proto-oncogene b.
   
  
 0.490
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.