STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fkbp2Peptidylprolyl isomerase. (84 aa)    
Predicted Functional Partners:
atp11b
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
   
 
 0.827
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 
 0.701
fxr1
Fragile X mental retardation, autosomal homolog 1.
      
 0.628
dnajc19
DnaJ (Hsp40) homolog, subfamily C, member 19.
   
  
 0.576
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.486
Sox2
SRY-box transcription factor 2.
   
  
 0.474
hyou1
Hypoxia up-regulated 1.
   
 0.462
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.460
trap1
TNF receptor-associated protein 1.
   
 0.460
hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
   
 0.460
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.