STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pemtPhosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (244 aa)    
Predicted Functional Partners:
LOC103464802
Choline/ethanolamine phosphotransferase 1b; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.964
chpt1
Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.954
selenoi
Selenoprotein I; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.949
lcat
Lecithin-cholesterol acyltransferase.
   
 0.942
lpcat2
Lysophosphatidylcholine acyltransferase 2.
     
 0.932
ENSPREP00000005506
Uncharacterized protein.
    
 0.928
mboat2
Membrane bound O-acyltransferase domain containing 2a; Belongs to the membrane-bound acyltransferase family.
    
 0.928
LOC103478598
Phosphatidylserine synthase 1a.
     
 0.927
lpcat3
Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.
     
 0.910
LOC103463466
Uncharacterized protein.
   
 
 0.904
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.