STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1272 aa)    
Predicted Functional Partners:
LOC103463549
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.958
LOC103470235
Uncharacterized protein.
    
 0.958
LOC103465516
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 0.947
LOC103473464
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.946
LOC103473465
G protein subunit alpha q.
    
 0.946
LOC103466076
Uncharacterized protein.
   
 0.939
LOC103459297
Uncharacterized protein.
   
 0.932
LOC103462546
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.
   
 0.925
LOC103464538
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
   
 0.925
LOC103465228
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
   
 0.925
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.