STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vav2Vav 2 guanine nucleotide exchange factor. (793 aa)    
Predicted Functional Partners:
LOC103479675
Rac family small GTPase 2.
   
 0.959
LOC103482188
Rac family small GTPase 3b.
   
 0.958
RAC1
Rac family small GTPase 1.
   
 0.958
LOC103481975
Uncharacterized protein.
   
 0.958
pik3r3
Uncharacterized protein.
    
0.933
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
0.933
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
0.933
LOC103478998
Uncharacterized protein.
    
 
0.932
LOC103463319
Uncharacterized protein.
    
 
0.932
LOC103475907
Zgc:158659; Belongs to the PI3/PI4-kinase family.
   
 
 0.927
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.