STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vps35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (798 aa)    
Predicted Functional Partners:
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.999
vps26a
VPS26, retromer complex component A.
   
 0.998
snx3
Sorting nexin 3.
   
 0.986
LOC103476205
Uncharacterized protein.
   
 0.979
vps26b
VPS26, retromer complex component B.
   
 0.979
snx2
Sorting nexin 2.
   
 0.946
snx1
Sorting nexin 1b.
   
 0.933
LOC103465960
Sorting nexin 1a.
   
 0.933
LOC103472200
Sorting nexin 10a.
   
 0.928
LOC103478580
Sorting nexin 10b.
   
 0.928
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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