STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Phf20Uncharacterized protein. (94 aa)    
Predicted Functional Partners:
mcrs1
Microspherule protein 1.
   
 0.929
kansl2
KAT8 regulatory NSL complex subunit 2.
    
 0.891
kansl3
KAT8 regulatory NSL complex subunit 3.
    
 0.878
wdr5
WD repeat domain 5.
    
 0.763
Tex30
Testis expressed 30.
    
 0.759
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.752
suds3
SDS3 homolog, SIN3A corepressor complex component.
   
 
 0.751
kansl1
KAT8 regulatory NSL complex subunit 1a.
    
 0.749
kansl1l
KAT8 regulatory NSL complex subunit 1-like.
    
 0.749
ogt
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1.
   
 0.729
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.