STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vegfcVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (420 aa)    
Predicted Functional Partners:
flt4
Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.957
flt1
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.957
LOC103471632
Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.942
kdr
Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.939
pdgfra
Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.878
vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
     
0.776
LOC103469672
Fibroblast growth factor receptor.
    
 0.742
LOC103458160
Fibroblast growth factor receptor.
    
 0.742
LOC103477293
Fibroblast growth factor receptor.
    
 0.742
LOC103473157
Fibroblast growth factor receptor.
    
 0.739
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.